JPH0133085B2 - - Google Patents

Info

Publication number
JPH0133085B2
JPH0133085B2 JP56125002A JP12500281A JPH0133085B2 JP H0133085 B2 JPH0133085 B2 JP H0133085B2 JP 56125002 A JP56125002 A JP 56125002A JP 12500281 A JP12500281 A JP 12500281A JP H0133085 B2 JPH0133085 B2 JP H0133085B2
Authority
JP
Japan
Prior art keywords
tablets
treatment
nephritis
chronic nephritis
units
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56125002A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5826822A (ja
Inventor
Shigemi Fujisaki
Mitsuaki Mitani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KAKEN SEIYAKU KK
Original Assignee
KAKEN SEIYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14899442&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0133085(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by KAKEN SEIYAKU KK filed Critical KAKEN SEIYAKU KK
Priority to JP56125002A priority Critical patent/JPS5826822A/ja
Priority to AU85792/82A priority patent/AU558711B2/en
Priority to EP82107092A priority patent/EP0072947B2/en
Priority to DE8282107092T priority patent/DE3271549D1/de
Priority to AT82107092T priority patent/ATE20185T1/de
Priority to US06/405,770 priority patent/US4485095A/en
Priority to DD82242397A priority patent/DD202804A5/de
Publication of JPS5826822A publication Critical patent/JPS5826822A/ja
Publication of JPH0133085B2 publication Critical patent/JPH0133085B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21081—Streptogrisin B (3.4.21.81)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP56125002A 1981-08-10 1981-08-10 慢性腎炎治療剤 Granted JPS5826822A (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP56125002A JPS5826822A (ja) 1981-08-10 1981-08-10 慢性腎炎治療剤
AU85792/82A AU558711B2 (en) 1981-08-10 1982-07-09 Enzyme preparation for treatment of liver and kidney disease
EP82107092A EP0072947B2 (en) 1981-08-10 1982-08-05 Agent for the prevention and treatment of liver diseases
DE8282107092T DE3271549D1 (en) 1981-08-10 1982-08-05 Agent for the prevention and treatment of liver and kidney diseases
AT82107092T ATE20185T1 (de) 1981-08-10 1982-08-05 Mittel zur verhuetung und behandlung von leberund nierenkrankheiten.
US06/405,770 US4485095A (en) 1981-08-10 1982-08-06 Pronase used for the treatment of diseases of the liver and kidneys in humans and animals
DD82242397A DD202804A5 (de) 1981-08-10 1982-08-10 Verfahren zur herstellung eines mittels zur vorbeugung und behandlung von leber- und nierenerkrankungen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56125002A JPS5826822A (ja) 1981-08-10 1981-08-10 慢性腎炎治療剤

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP61141773A Division JPS61293927A (ja) 1986-06-18 1986-06-18 肝臓疾患予防治療剤
JP61141772A Division JPS61293928A (ja) 1986-06-18 1986-06-18 腎ネフロ−ゼ治療剤

Publications (2)

Publication Number Publication Date
JPS5826822A JPS5826822A (ja) 1983-02-17
JPH0133085B2 true JPH0133085B2 (en]) 1989-07-11

Family

ID=14899442

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56125002A Granted JPS5826822A (ja) 1981-08-10 1981-08-10 慢性腎炎治療剤

Country Status (7)

Country Link
US (1) US4485095A (en])
EP (1) EP0072947B2 (en])
JP (1) JPS5826822A (en])
AT (1) ATE20185T1 (en])
AU (1) AU558711B2 (en])
DD (1) DD202804A5 (en])
DE (1) DE3271549D1 (en])

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4844897A (en) * 1985-09-13 1989-07-04 Hiroshi Maeda Anti-tumor protease preparations
JPS62215533A (ja) * 1986-03-17 1987-09-22 Shigemi Fujisaki 膠原病又は関節リウマチの予防治療剤
JPS61293928A (ja) * 1986-06-18 1986-12-24 Kaken Pharmaceut Co Ltd 腎ネフロ−ゼ治療剤
EP0309602B1 (de) * 1987-09-30 1993-03-24 MUCOS EMULSIONSGESELLSCHAFT m.b.H. Verwendung katabolischer Enzyme zur Herstellung eines Medikaments zum Bekämpfen der erworbenen Immunschwäche (AIDS) und deren Vorstadien (LAS, ARC)
JP3054190B2 (ja) 1989-01-27 2000-06-19 イムノリティックス・インコーポレイテッド 良性前立腺肥大処置のための組成物および方法
US5116615A (en) * 1989-01-27 1992-05-26 Immunolytics, Inc. Method for treating benign prostatic hypertrophy
JPH02292226A (ja) * 1989-05-08 1990-12-03 Shigemi Fujisaki 障害された神経細胞賦活予防治療剤
NL9201842A (nl) * 1992-10-23 1994-05-16 Teng Hian Khoe Toepassing van een papaine bevattend voedingssupplement voor therapeutische behandeling van AIDS aandoeningen.
US5639934A (en) * 1993-04-01 1997-06-17 Nakamichi Yamasaki Process for the desulfurization of sulfur-containing compositions by hydrothermal reaction
JP2673417B2 (ja) * 1994-08-03 1997-11-05 茂巳 藤崎 Ｂ型肝炎又はｃ型肝炎のウイルス性疾患の予防治療剤
US5814328A (en) 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
US20020102253A1 (en) * 1997-02-25 2002-08-01 Mynott Tracey Lehanne Component of bromelain
DE19726253C2 (de) * 1997-06-20 2000-03-16 Mucos Pharma Gmbh & Co Verwendung von mindestens einem proteolytischen Enzym und Rutosid zur Behandlung von Glomerulonephritis
GB9713667D0 (en) * 1997-06-27 1997-09-03 Cortecs Ltd Enhancement of intestinal permeability
JP2002087990A (ja) * 2000-09-18 2002-03-27 Shigemi Fujisaki エイズ、ｂ型肝炎、ｃ型肝炎、インフルエンザなどのウイルス性疾患予防治療剤
WO2003066088A2 (de) * 2002-02-06 2003-08-14 Trommsdorff Gmbh & Co. Kg Arzneimittel Protease-screening und neue verwendung von proteasen
AUPS242702A0 (en) * 2002-05-21 2002-06-13 Colltech Australia Limited Improved method for the extraction and purification of collagen
US8710012B2 (en) 2003-07-14 2014-04-29 Cls Therapeutics Limited Method for treating oncological diseases
US8388951B2 (en) 2003-07-14 2013-03-05 Cls Therapeutics Limited Method for treating systemic DNA mutation disease
US8431123B2 (en) 2003-07-14 2013-04-30 Cls Therapeutics Limited Method for treating systemic bacterial, fungal and protozoan infection
AU2004285558A1 (en) * 2003-10-29 2005-05-12 Altus Pharmaceuticals Inc. Non-pancreatic proteases for controlling plasma cholecystokinin (CCK) concentration and for treating pain
US8916151B2 (en) * 2005-04-25 2014-12-23 Cls Therapeutics Limited Method for treating a reduction of fertility
WO2008066403A1 (en) * 2006-11-28 2008-06-05 Dmitry Dmitrievich Genkin Method for treating human diseases associated with an increased deoxyribonucleic acid content in extracellular spaces of tissues and a medicinal preparation for carrying out said method
UA28103U (uk) 2007-07-12 2007-11-26 Ольга Олександрівна Біляєва Комплексний сорбційно-протеолітичний препарат сертасил для лікування гнійних ран, трофічних виразок, опіків
WO2010079209A2 (en) * 2009-01-08 2010-07-15 Golub Alexandr A Compositions for treating wounds and skin conditions
US10086053B2 (en) 2012-12-06 2018-10-02 Giuseppe CARPIGNOLI Therapeutic vegetable substances
ITTO20121050A1 (it) * 2012-12-06 2014-06-07 Giuseppe Carpignoli Sostanze vegetali ad effetto curativo
US10617743B2 (en) 2014-06-19 2020-04-14 Cls Therapeutics Limited Method to improve safety and efficacy of anti-cancer therapy
ES2799515T3 (es) 2015-05-22 2020-12-18 Dmitry Dmitrievich Genkin ADN extracelular como una diana terapéutica en la neurodegeneración
US11905522B2 (en) 2018-01-16 2024-02-20 Cls Therapeutics Limited Treatment of diseases by liver expression of an enzyme which has a deoxyribonuclease (DNase) activity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2073659A (en) * 1933-12-13 1937-03-16 Ernest K Stratton Medicinal compounds
US3004893A (en) * 1959-10-21 1961-10-17 Richardson Merrell Inc Enteric coated trypsin and chymotrypsin anti-inflammatory compositions
FR2603M (fr) * 1962-01-22 1964-06-22 Roussel Uclaf Nouveau médicament notamment pour le traitement des dégénérescences hépatiques d'origine chimique, bactérienne, toxique ou sénile.
US3324002A (en) * 1962-09-17 1967-06-06 Armour Pharma Anti-inflammatory preparations containing proteolytic enzymes and adrenal glucocorticoids
FR3536M (en]) * 1964-06-16 1965-09-13 Mauvernay Roland Yves
BE684147A (en]) * 1965-07-22 1966-12-16
LU59502A1 (en]) * 1969-09-24 1970-02-26
US3819830A (en) * 1971-07-01 1974-06-25 Dainippon Pharmaceutical Co Method for treating diseases by coenzyme a and adenosine triphosphate and composition therefor
FR2448903A1 (fr) * 1979-02-19 1980-09-12 Martin Henri Medicament nouveau a base d'agents antimicrobiens, d'enzymes, d'anti-inflammatoires, d'anesthesique local, d'agents keratolytiques, d'agents mucolytiques et d'au moins un emulsionnant

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
THROMBOSIS AND HAEMOSTASIS=1977 *
VESTNIK AKADEMII MEDITSINSKIKH NAUK S S S R=1970 *

Also Published As

Publication number Publication date
EP0072947A2 (en) 1983-03-02
ATE20185T1 (de) 1986-06-15
EP0072947A3 (en) 1983-07-27
DE3271549D1 (en) 1986-07-10
DD202804A5 (de) 1983-10-05
JPS5826822A (ja) 1983-02-17
AU558711B2 (en) 1987-02-05
EP0072947B1 (en) 1986-06-04
AU8579282A (en) 1983-02-17
EP0072947B2 (en) 1994-01-12
US4485095A (en) 1984-11-27

Similar Documents

Publication Publication Date Title
JPH0133085B2 (en])
JPH0552814B2 (en])
US5518729A (en) Compositions and methods for reparation and prevention of fibrotic lesions
EP0702551B1 (en) Compositions and methods for reparation and prevention of fibrotic lesions
US10806735B2 (en) Use of neutrophil elastase inhibitors in liver disease
US3224942A (en) Anti-inflammatory, anti-edema and anti-thrombi drug
JPS61293927A (ja) 肝臓疾患予防治療剤
Kampmann et al. Ampicillin and propylthiouracil pharmacokinetics in intestinal bypass patients followed up to a year after operation
Mammdoh et al. Evaluation of anti-inflammatory effect of topical serratiopeptidase in mice
US5206017A (en) Use of protease nexin-I as an antiinflammatory
JPS58189122A (ja) 高脂血症予防治療剤
JPS59225122A (ja) 悪液質治療改善剤
CN105944078A (zh) 一种用于治疗慢性肾盂肾炎的复方护理剂及其制备方法
JPS608227A (ja) 抗アレルギ−増強剤
JPH0351691B2 (en])
EP3758702A1 (en) Treatment of hereditary angioedema
RU2068698C1 (ru) Лекарственное средство для лечения больных со сниженной внешнесекреторной функцией поджелудочной железы
JPS62215533A (ja) 膠原病又は関節リウマチの予防治療剤
Moshal Nutrizym as a pancreatic enzyme replacement
JPS62205033A (ja) 関節リウマチ治療剤
Laake Enzymic drugs
DE10141198A1 (de) Prophylaktisches und therapeutisches antivirales Medikament gegen Aids, Hepatitis B, Hepatitis C und Influenza
SU1284553A1 (ru) Способ лечени хронического гломерулонефрита нефротического типа
RU2171688C2 (ru) Способ лечения реактивного панкреатита у детей
Mbanefo et al. MP47-11 DOWNREGULATION OF PRO-INFLAMMATORY PATHWAYS BY IPSE, A UROGENITAL PARASITE-DERIVED IMMUNOMODULATORY PROTEIN, REDUCES IFOSFAMIDE-INDUCED HEMORRHAGIC CYSTITIS